Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647364 | 1.00 | GCGR (0.42) | GCGRBRD4MCL1 | |
| SCHEMBL2648438 | 0.91 | GCGR (0.44) | GCGR | |
| SCHEMBL2654624 | 0.90 | GCGR (0.49) | GCGR | |
| SCHEMBL2647812 | 0.87 | GCGR (0.45) | GCGR | |
| SCHEMBL2647814 | 0.87 | GCGR (0.45) | GCGR | |
| SCHEMBL2647952 | 0.86 | GCGR (0.42) | GCGRBRD4MCL1 | |
| SCHEMBL2647951 | 0.86 | GCGR (0.42) | GCGRBRD4MCL1 | |
| SCHEMBL2648021 | 0.85 | GCGR (0.47) | GCGR | |
| SCHEMBL2648024 | 0.85 | GCGR (0.47) | GCGR | |
| SCHEMBL2648266 | 0.82 | GCGR (0.49) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |