SCHEMBL2654624

SCHEMBL2654624

CCCC=Cc1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccccc1OCc1ccccc1.CCCCCc1c(C(C)C)nc(C(C)C)c(C=O)c1-c1ccccc1OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2647364 0.90 GCGR (0.42) GCGR
SCHEMBL2648040 0.90 GCGR (0.42) GCGR
SCHEMBL2647675 0.89 GCGR (0.47) GCGR
SCHEMBL2648438 0.82 GCGR (0.44) GCGR
SCHEMBL2647814 0.78 GCGR (0.45) GCGR
SCHEMBL2647812 0.78 GCGR (0.45) GCGR
SCHEMBL2647952 0.78 GCGR (0.42) GCGR
SCHEMBL2647951 0.78 GCGR (0.42) GCGR
SCHEMBL2648021 0.76 GCGR (0.47) GCGR
SCHEMBL2648024 0.76 GCGR (0.47) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934274-A1 SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS Bayer Corporation (US) 1999-08-11 EP disclosed
WO-1998004528-A2 SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS BAYER CORPORATION (US) 1998-02-05 WO disclosed