Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 3/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13829275 | 0.88 | CYP3A4 (0.62) | CYP3A4MAPTMAPK1THRBALOX15 | |
| SCHEMBL23202768 | 0.86 | CYP3A4 (0.56) | CYP3A4MAPTMAPK1THRBPTPN1 | |
| SCHEMBL26480861 | 0.80 | CYP3A4 (0.67) | CYP3A4MAPTMAPK1PTPN1CYP2C9 | |
| SCHEMBL21588204 | 0.80 | CYP3A4 (0.67) | CYP3A4MAPTMAPK1PTPN1CYP2C9 | |
| SCHEMBL12573080 | 0.78 | CYP3A4 (0.61) | CYP3A4MAPTMAPK1THRBALDH1A1 | |
| SCHEMBL26481102 | 0.77 | DPP4 (0.49) | CYP3A4MAPTMAPK1PTPN1CYP2C9 | |
| Catechin Tetramethylether SCHEMBL1430853 | 0.77 | CYP3A4 (0.81) | CYP3A4MAPTMAPK1THRBALDH1A1 | |
| Catechin Tetramethylether SCHEMBL30178011 | 0.77 | CYP3A4 (0.81) | CYP3A4MAPTMAPK1THRBALDH1A1 | |
| Catechin Tetramethylether SCHEMBL30991591 | 0.77 | CYP3A4 (0.81) | CYP3A4MAPTMAPK1THRBALDH1A1 | |
| Catechin Tetramethylether SCHEMBL28731348 | 0.77 | CYP3A4 (0.81) | CYP3A4MAPTMAPK1THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643405-B2 | Compound for treatment or prevention of liver diseases | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2023-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11643405-B2 | Compound for treatment or prevention of liver diseases | SLC10A1, GYS2, CPT1A | CYP3A4 187/4885MAPT 1807/4885MAPK1 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.