SCHEMBL2648313

SCHEMBL2648313

CCOC(=O)c1c(C(C)C)nc(C(C)C)c(CCO)c1-c1ccc(F)cc1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2647286 0.91 GCGR (0.79) GCGR
SCHEMBL2648212 0.88 GCGR (0.62) GCGR
SCHEMBL9268564 0.88 GCGR (0.64) GCGR
SCHEMBL7560766 0.87 GCGR (0.65) GCGR
SCHEMBL2662930 0.87 GCGR (0.62) GCGR
SCHEMBL9269768 0.87 GCGR (0.62) GCGR
SCHEMBL2649345 0.85 GCGR (0.67) GCGR
SCHEMBL2648326 0.83 GCGR (0.66) GCGR
SCHEMBL9269271 0.82 GCGR (0.57) GCGR
SCHEMBL2648227 0.82 GCGR (0.60) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934274-A1 SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS Bayer Corporation (US) 1999-08-11 EP disclosed
WO-1998004528-A2 SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS BAYER CORPORATION (US) 1998-02-05 WO disclosed