Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647286 | 0.90 | GCGR (0.79) | GCGR | |
| SCHEMBL2648212 | 0.89 | GCGR (0.62) | GCGRALDH1A1L3MBTL1 | |
| SCHEMBL2648313 | 0.88 | GCGR (0.65) | GCGR | |
| SCHEMBL7560766 | 0.88 | GCGR (0.65) | GCGR | |
| SCHEMBL2662930 | 0.88 | GCGR (0.62) | GCGR | |
| SCHEMBL9269768 | 0.88 | GCGR (0.62) | GCGR | |
| SCHEMBL2649345 | 0.84 | GCGR (0.67) | GCGRALDH1A1L3MBTL1 | |
| SCHEMBL9269271 | 0.83 | GCGR (0.57) | GCGRALDH1A1 | |
| SCHEMBL2648227 | 0.83 | GCGR (0.60) | GCGRALDH1A1L3MBTL1 | |
| SCHEMBL2647300 | 0.82 | GCGR (0.56) | GCGRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401746-A | FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND HMG-COA REDUCTASE | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| US-5169857-A | Anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |
| US-5006530-A | Certain 7-[2,6-diisopropyl-4-phenyl-5-lower alkoxymethyl-pyrid-3-yl]-3,5-dihydroxy-6-enoates and derivatives useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |