Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649234 | 0.88 | MAPT (0.52) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2648721 | 0.85 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2648482 | 0.84 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2650623 | 0.82 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2649683 | 0.82 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2656495 | 0.80 | ALDH1A1 (0.48) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2654223 | 0.80 | AKR1C3 (0.60) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2654961 | 0.78 | AKR1C3 (0.47) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2655113 | 0.77 | AKR1B1 (0.59) | MAPTMEN1KMT2AHTTMAPK1 | |
| SCHEMBL5781737 | 0.77 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934281-A1 | 1-PHENYL-BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS BAGA- A? RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017651-A1 | 1-PHENYL-BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS BAGA-A RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 1998-04-30 | — | — | WO | disclosed |