Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 16/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26485809 | 0.87 | MAT2A (0.49) | MAT2ACYP11B1CYP11B2 | |
| SCHEMBL31026808 | 0.87 | MAT2A (0.49) | MAT2ACYP11B1CYP11B2 | |
| SCHEMBL26489377 | 0.86 | MAT2A (0.46) | MAT2APRMT5CYP3A4 | |
| SCHEMBL26485646 | 0.86 | MAT2A (0.39) | MAT2APRMT5CYP3A4TRPV1 | |
| SCHEMBL30420090 | 0.86 | MAT2A (0.67) | MAT2APRMT5CYP3A4 | |
| SCHEMBL26484971 | 0.86 | MAT2A (0.67) | MAT2APRMT5CYP3A4 | |
| SCHEMBL26485808 | 0.83 | MAT2A (0.50) | MAT2APRMT5 | |
| SCHEMBL26488687 | 0.83 | MAT2A (0.39) | MAT2APRMT5CYP3A4PIK3CD | |
| SCHEMBL30420483 | 0.83 | MAT2A (0.39) | MAT2APRMT5CYP3A4PIK3CD | |
| SCHEMBL30419923 | 0.82 | MAT2A (0.54) | MAT2APRMT5CYP3A4PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066283-A1 | METHIONINE ADENOSYLTRANSFERASE 2A (MAT2A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-04-27 | — | — | WO | disclosed |