Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435255 | 0.76 | CYP4F2 (0.63) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL2302173 | 0.74 | CYP4F2 (0.69) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL12035852 | 0.74 | CYP4F2 (0.60) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL2650308 | 0.73 | CYP4F2 (0.58) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL2664362 | 0.72 | NPC1 (0.42) | CYP3A4CYP2C9CYP2C19LMNAKDM4E | |
| SCHEMBL2651047 | 0.72 | NPC1 (0.42) | CYP3A4CYP2C9CYP2C19LMNAKDM4E | |
| SCHEMBL69660 | 0.72 | CYP4F2 (0.86) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL21350641 | 0.71 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL27674003 | 0.70 | CYP4F2 (0.65) | CYP4F2CYP4A11ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22098182 | 0.70 | CYP4F2 (1.00) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |