Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL7798417 | 0.80 | MEN1 (0.42) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL2647106 | 0.79 | CYP2A6 (0.53) | CA2CA1CA9MEN1KMT2A | |
| SCHEMBL9005 | 0.77 | MEN1 (0.57) | ERN1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL35849993 | 0.77 | MEN1 (0.57) | ERN1MEN1KMT2AALDH1A1POLB | |
| Sulfuric Acid SCHEMBL18007425 | 0.76 | ERN1 (0.48) | CA2CA1CA9ERN1MEN1 | |
| SCHEMBL11132298 | 0.75 | MEN1 (0.55) | ERN1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL3109583 | 0.75 | MEN1 (0.55) | ERN1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL3107253 | 0.75 | MEN1 (0.55) | ERN1MEN1KMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL10384676 | 0.75 | MEN1 (0.55) | ERN1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL3115624 | 0.75 | MEN1 (0.55) | ERN1MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | disclosed |