Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL7802630 | 0.89 | PPARG (0.44) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| Cyclohexylamine SCHEMBL8039053 | 0.84 | GRIK1 (0.46) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| Cyclohexylamine SCHEMBL8039051 | 0.84 | GRIK1 (0.46) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL35849993 | 0.80 | MEN1 (0.57) | MEN1KMT2AALDH1A1POLBGRIN2D | |
| SCHEMBL9005 | 0.80 | MEN1 (0.57) | MEN1KMT2AALDH1A1POLBGRIN2D | |
| SCHEMBL2648658 | 0.80 | CA2 (0.40) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| Lysine SCHEMBL8035117 | 0.80 | PPARG (0.42) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| Lysine SCHEMBL8035120 | 0.80 | PPARG (0.42) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL11132298 | 0.78 | MEN1 (0.55) | MEN1KMT2AALDH1A1POLBGRIN2D | |
| SCHEMBL3107253 | 0.78 | MEN1 (0.55) | MEN1KMT2AALDH1A1POLBGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |