Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | CASP6 | P55212 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29441750 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL29441752 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL7358453 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL5066497 | 0.80 | ALDH1A1 (0.71) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL28966319 | 0.79 | KMT2A (0.59) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL4206904 | 0.78 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL6287959 | 0.78 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL29580629 | 0.78 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL5694486 | 0.78 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL10824680 | 0.78 | KDM4E (0.69) | ALDH1A1KDM4EGAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |