Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A15 | Q9H2J7 | 14/20 | 0.79 |
| ▸ | HRH1 | P35367 | 7/20 | 0.79 |
| ▸ | PTAFR | P25105 | 3/20 | 0.79 |
| ▸ | FNTA | P49354 | 3/20 | 0.79 |
| ▸ | FNTB | P49356 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.72 |
| ▸ | GMNN | O75496 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.72 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.72 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sch-37370 SCHEMBL29626524 | 0.89 | PTAFR (1.00) | SLC6A15HRH1PTAFRFNTAFNTB | |
| Sch-37370 SCHEMBL29754039 | 0.89 | PTAFR (1.00) | SLC6A15HRH1PTAFRFNTAFNTB | |
| Sch-37370 SCHEMBL3071641 | 0.89 | PTAFR (1.00) | SLC6A15HRH1PTAFRFNTAFNTB | |
| SCHEMBL4460572 | 0.88 | HRH1 (0.82) | SLC6A15HRH1PTAFRFNTAFNTB | |
| SCHEMBL31384618 | 0.88 | HRH1 (0.82) | SLC6A15HRH1PTAFRFNTAFNTB | |
| SCHEMBL29626502 | 0.88 | HRH1 (0.82) | SLC6A15HRH1PTAFRFNTAFNTB | |
| SCHEMBL8878121 | 0.88 | SLC6A15 (0.86) | SLC6A15HRH1PTAFRFNTAFNTB | |
| SCHEMBL3367280 | 0.87 | SLC6A15 (0.82) | SLC6A15HRH1PTAFRFNTAFNTB | |
| SCHEMBL8878015 | 0.86 | SLC6A15 (0.86) | SLC6A15HRH1PTAFRFNTAFNTB | |
| SCHEMBL8877813 | 0.86 | SLC6A15 (0.79) | SLC6A15HRH1PTAFRFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023071601-A1 | DESLORATADINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 天津市昕晨投资发展有限公司 | 2023-05-04 | — | — | WO | disclosed |