SCHEMBL26488593

SCHEMBL26488593

CCCCCCCCCCCCC1(CCCCCCCCCCCC)c2cc(BO)ccc2-c2ccc(BO)cc21

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.35
CNR2 P34972 3/20 0.35
MMP2 P08253 4/20 0.33
MMP9 P14780 4/20 0.33
MMP8 P22894 4/20 0.33
MMP13 P45452 4/20 0.33
PDK2 Q15119 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26488594 1.00 CNR1 (0.35) CNR1CNR2MMP2MMP9MMP8
SCHEMBL24285478 0.93 PDK2 (0.40) CNR1CNR2MMP2MMP9MMP8
SCHEMBL28386971 0.93 PDK2 (0.40) CNR1CNR2MMP2MMP9MMP8
SCHEMBL26489849 0.89 CNR1 (0.30) CNR1CNR2
SCHEMBL12962387 0.89 LIPG (0.38) CNR1CNR2
SCHEMBL29272574 0.79 TP53 (0.45) CNR1CNR2
SCHEMBL28852732 0.79 TP53 (0.45) CNR1CNR2
SCHEMBL16261010 0.78 PDK2 (0.33) CNR1CNR2PDK2
SCHEMBL21531690 0.78 PDK2 (0.33) CNR1CNR2PDK2
SCHEMBL19442933 0.77 CNR1 (0.40) CNR1CNR2MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 US disclosed
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS PHOSPHO1, SGMS1, PLIN3 CNR1 3929/4885CNR2 4312/4885MMP2 3369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.