Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649001 | 0.94 | FFAR1 (0.38) | POLBCSF1RMAPK14MAPK13 | |
| SCHEMBL1343698 | 0.88 | POLB (0.38) | POLBCSF1RMAPK14MAPK13MAPT | |
| SCHEMBL1343911 | 0.87 | FFAR1 (0.42) | POLBCSF1RMAPK14MAPK13MAPT | |
| SCHEMBL2662425 | 0.83 | SIRT2 (0.36) | MAPK14MAPK13MAPTSIRT2LMNA | |
| SCHEMBL1343996 | 0.83 | POLB (0.39) | POLBCSF1RMAPK14MAPTSIRT2 | |
| SCHEMBL1342314 | 0.82 | POLB (0.42) | POLBCSF1RMAPK14MAPK13MAPT | |
| SCHEMBL1342117 | 0.82 | SMN1; SMN2 (0.45) | POLBMAPTLMNATP53MEN1 | |
| SCHEMBL1342664 | 0.81 | POLB (0.41) | POLBMAPK14MAPK13MAPTTP53 | |
| SCHEMBL1341813 | 0.81 | POLB (0.43) | POLBMAPTLMNATP53MEN1 | |
| SCHEMBL1343098 | 0.81 | POLB (0.44) | POLBMAPK14MAPK13MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |