SCHEMBL26490959

SCHEMBL26490959

Fc1ccc(NC(=S)NCc2ccccc2)cc1C(F)(F)F

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.65
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
ALDH1A1 P00352 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
GAA P10253 3/20 0.65
HPGD P15428 4/20 0.64
MYC P01106 1/20 0.64
MAX P61244 1/20 0.64
RAB9A P51151 2/20 0.59
NPC1 O15118 1/20 0.59
NPSR1 Q6W5P4 3/20 0.58
LMNA P02545 3/20 0.58
MAOB P27338 3/20 0.58
PLA2G1B P04054 2/20 0.58
ATG4B Q9Y4P1 2/20 0.58
MAOA P21397 1/20 0.57
ATM Q13315 1/20 0.57
HTT P42858 2/20 0.57
ALOX12 P18054 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4343714 0.80 RAB9A (0.63) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL7569031 0.80 PTPN7 (0.54) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL18695140 0.79 MAPT (1.00) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL6816225 0.79 KMT2A (0.52) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL1419684 0.79 AR (0.54) MAPTMEN1KMT2APLA2G1BATG4B
SCHEMBL22289498 0.78 MAPT (1.00) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL3299625 0.78 MYC (1.00) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL8612547 0.78 MAOB (0.92) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL18807464 0.77 MAOB (0.88) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL8613032 0.77 MAOB (0.83) MAPTMEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134821-A1 MYC-MAX INHIBITOR COMPOUND THERAPEUTICS FOR CANCER TREATMENT, METHODS AND USES ASSOCIATED THEREWITH THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134821-A1 MYC-MAX INHIBITOR COMPOUND THERAPEUTICS FOR CANCER TREATMENT, METHODS AND USES ASSOCIATED THEREWITH MYC, MYCBP, MAX MAPT 297/4885MEN1 6/4885KMT2A 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.