Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCYAP1R1 | P41586 | 8/20 | 0.65 |
| ▸ | GCGR | P47871 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649190 | 1.00 | ADCYAP1R1 (0.65) | ADCYAP1R1GCGRKDM4EMAPTMEN1 | |
| SCHEMBL9071643 | 0.83 | GCGR (0.63) | ADCYAP1R1GCGR | |
| SCHEMBL2649370 | 0.78 | GCGR (0.61) | ADCYAP1R1GCGRKDM4EMAPTMEN1 | |
| SCHEMBL2663729 | 0.77 | ADCYAP1R1 (0.71) | ADCYAP1R1GCGR | |
| SCHEMBL9072061 | 0.76 | GCGR (1.00) | ADCYAP1R1GCGR | |
| SCHEMBL28521566 | 0.74 | GAA (0.75) | ADCYAP1R1GCGRKDM4EMAPTMEN1 | |
| SCHEMBL11974463 | 0.74 | GAA (0.68) | GCGRKDM4EMAPTMEN1KMT2A | |
| SCHEMBL7228192 | 0.74 | GCGR (0.68) | ADCYAP1R1GCGRMAPTMEN1KMT2A | |
| SCHEMBL9072060 | 0.74 | GCGR (0.60) | ADCYAP1R1GCGRKDM4EMAPTMEN1 | |
| SCHEMBL2664303 | 0.73 | GCGR (1.00) | ADCYAP1R1GCGRKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |