Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.50 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649264 | 1.00 | GCGR (0.50) | GCGRSLC10A2ESR1HMGCRCHRM1 | |
| SCHEMBL2649395 | 0.93 | GCGR (0.47) | GCGRSLC10A2MEN1ALDH1A1MAPT | |
| SCHEMBL2649396 | 0.93 | GCGR (0.47) | GCGRSLC10A2MEN1ALDH1A1MAPT | |
| SCHEMBL2647468 | 0.92 | SLC10A2 (0.44) | GCGRSLC10A2MEN1ALDH1A1MAPT | |
| SCHEMBL2647466 | 0.92 | SLC10A2 (0.44) | GCGRSLC10A2MEN1ALDH1A1MAPT | |
| SCHEMBL2650698 | 0.91 | SLC10A2 (0.43) | GCGRSLC10A2ESR1HMGCRCHRM1 | |
| SCHEMBL2649455 | 0.91 | SLC10A2 (0.43) | GCGRSLC10A2ESR1HMGCRCHRM1 | |
| SCHEMBL2647327 | 0.91 | SLC10A2 (0.43) | GCGRSLC10A2MEN1ALDH1A1MAPT | |
| SCHEMBL2648214 | 0.90 | MAPT (0.48) | SLC10A2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2648215 | 0.90 | MAPT (0.48) | SLC10A2MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |