Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 9/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.53 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 7/20 | 0.50 |
| ▸ | BCHE | P06276 | 6/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25318996 | 0.94 | EPHX2 (0.52) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL27384090 | 0.94 | EPHX2 (0.52) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL22515605 | 0.90 | EPHX2 (0.59) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL8955670 | 0.88 | EPHX2 (0.62) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL8955664 | 0.88 | EPHX2 (0.62) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL8955557 | 0.88 | EPHX2 (0.62) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL8955590 | 0.88 | EPHX2 (0.62) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL8955676 | 0.88 | EPHX2 (0.62) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL31418688 | 0.88 | EPHX2 (0.47) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL6852352 | 0.88 | CNR1 (0.66) | EPHX2CNR1KDM5AKDM4CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3736261-B1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX INC (US) | 2023-10-11 | — | — | EP | disclosed |