Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 7/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.49 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955676 | 1.00 | EPHX2 (0.62) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL8955590 | 1.00 | EPHX2 (0.62) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL8955664 | 1.00 | EPHX2 (0.62) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL8955670 | 1.00 | EPHX2 (0.62) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL22986027 | 0.94 | EPHX2 (0.59) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL22986032 | 0.94 | EPHX2 (0.59) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL23343387 | 0.92 | EPHX2 (0.70) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL21596652 | 0.92 | EPHX2 (0.70) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL5284897 | 0.92 | EPHX2 (0.70) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL11702777 | 0.92 | EPHX2 (0.70) | EPHX2CNR1KDM5AKDM4CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |