SCHEMBL26495

SCHEMBL26495

Oc1cccc2[nH]ccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.56
CYP1A2 P05177 2/20 0.55
HPGD P15428 2/20 0.55
HSD17B10 Q99714 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
CYP3A4 P08684 1/20 0.55
PARP1 P09874 1/20 0.55
CYP2C9 P11712 1/20 0.55
RAB9A P51151 1/20 0.55
BLM P54132 1/20 0.55
PARP15 Q460N3 1/20 0.55
MAPK1 P28482 1/20 0.47
PIK3CD O00329 1/20 0.46
RHEB Q15382 6/20 0.43
ADRB1 P08588 1/20 0.43
HTR6 P50406 1/20 0.43
DAO P14920 1/20 0.42
ASH1L Q9NR48 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363007 1.00 AHR (0.56) AHRCYP1A2HPGDHSD17B10KDM4E
SCHEMBL9232128 1.00 AHR (0.56) AHRCYP1A2HPGDHSD17B10KDM4E
Iodide SCHEMBL30373944 0.98 AHR (0.54) AHRCYP1A2HPGDHSD17B10KDM4E
SCHEMBL25177318 0.98 AHR (0.54) AHRCYP1A2HPGDHSD17B10KDM4E
Hydrochloric Acid SCHEMBL8356509 0.98 AHR (0.54) AHRCYP1A2HPGDHSD17B10KDM4E
Fumaric Acid SCHEMBL29504141 0.85 ALDH1A1 (0.47) AHRCYP1A2HPGDHSD17B10KDM4E
SCHEMBL5464095 0.85 KDM4E (0.43) AHRCYP1A2HPGDHSD17B10KDM4E
Trifluoroacetic Acid SCHEMBL2936459 0.84 KDM4E (0.46) AHRCYP1A2HPGDHSD17B10KDM4E
SCHEMBL7147902 0.82 TYR (0.68) AHRCYP1A2HPGDHSD17B10KDM4E
SCHEMBL27504679 0.81 PIK3CD (0.51) AHRCYP1A2HPGDHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9993 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer HENKEL AG & CO. KGAA (DE) 2026-05-12 US claimed
US-12590060-B2 Scalable synthetic route for psilocin and psilocybin MINDSET PHARMA INC. (CA) 2026-03-31 US claimed
EP-4704837-A2 METHODS FOR USING BACTERIA AND HOST/MICROBIOTA-DERIVED METABOLITES FOR DIAGNOSIS AND TREATMENT OF ENDOMETRIOSIS Baylor College of Medicine (US) 2026-03-11 EP claimed
EP-4608363-A1 A COMPOSITION FOR IMPROVING EFFECTIVENESS OF DYE PRECURSORS FOR CHANGE OF COLOUR OF HAIR Cavinkare Pvt. Ltd (IN) 2025-09-03 EP claimed
US-12344708-B2 Tissue-adhesive hydrogels POLYGANICS IP B.V. (NL) 2025-07-01 US claimed
US-20250171815-A1 PRODUCTION OF PSYCHEDELIC COMPOUNDS CORE ONE LABS INC (CA) 2025-05-29 US claimed
WO-2025073360-A1 BIOCATALYTIC CASCADE FOR THE PRODUCTION OF TRYPTAMINE DERIVATIVES ENZYAN BIOCATALYSIS GMBH (AT) 2025-04-10 WO claimed
WO-2025061319-A2 IMPROVING THE WASHING FASTNESS OF LEVEL 2 COLORATIONS BY MEANS OF A SEALING PROCESS USING SILANES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO claimed
EP-4496559-A1 AGENT FOR OXIDATIVE DYEING OF KERATIN FIBRES, CONTAINING ISATIN AND AT LEAST ONE DEFINED POLYMER Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496557-A1 MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED COMPLEXING AGENT Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-0271186-A1 Hydroxyindoles and their use in dyeing REPLIGEN CORPORATION (US) 1988-06-15 EP claimed
US-4736043-A Process for the preparation of indole derivatives BOEHRINGER MANNEHEIM GMBH (DE) 1988-04-05 US claimed
EP-0166155-B1 2-ALKYLSULPHONYL-1,4-DIAMINOBENZENES, PROCESS FOR THEIR PREPARATION AND OXIDATIVE HAIR-DYEING COMPOSITIONS CONTAINING THESE COMPOUNDS Wella Aktiengesellschaft (DE) 1987-09-23 EP claimed
EP-0226072-A1 Oxidation dye containing 4-amino-2-aminomethyl phenol Wella Aktiengesellschaft (DE) 1987-06-24 EP claimed
WO-1987003475-A2 OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1987-06-18 WO claimed
EP-0081137-B1 PROCESS FOR THE PREPARATION OF INDOLE DERIVATIVES, THEIR USE AS INTERMEDIATES, AND 4-HYDROXY INDOLES Roche Diagnostics GmbH (DE) 1986-08-06 EP claimed
EP-0182187-A1 Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols Wella Aktiengesellschaft (DE) 1986-05-28 EP claimed
WO-1986002829-A1 OXIDATION-TYPE HAIR-DYEING MEANS BASED ON 4-AMINO-2-HYDROXYALKYL-PHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1986-05-22 WO claimed
WO-1986000303-A1 TWO-ALKYL-SULPHONYL-1,4-DIAMINOBENZENES, PREPARATION THEREOF AND UTILISATION THEREOF WELLA AKTIENGESELLSCHAFT (DE) 1986-01-16 WO claimed
EP-0166155-A1 2-Alkylsulphonyl-1,4-diaminobenzenes, process for their preparation and oxidative hair-dyeing compositions containing these compounds Wella Aktiengesellschaft (DE) 1986-01-02 EP claimed