SCHEMBL2649896

SCHEMBL2649896

CC1(Oc2ccccc2)C=CC=CC1N

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10946212 0.78
SCHEMBL27879155 0.76
SCHEMBL4096690 0.69 KDM1A (0.34)
SCHEMBL29093086 0.66 PLAU (0.35)
SCHEMBL4236763 0.63 MAOB (0.36)
SCHEMBL28537875 0.63 MAOB (0.36)
SCHEMBL11673779 0.62 PARP10 (0.31)
SCHEMBL29130612 0.62
SCHEMBL7256147 0.62
SCHEMBL1184894 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1531815-A1 GLUCOKINASE ACTIVATORS NOVO NORDISK A/S (DK) 2005-05-25 EP disclosed
WO-2004002481-A1 ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS NOVO NORDISK A/S (DK) 2004-01-08 WO disclosed