SCHEMBL4236763

SCHEMBL4236763

NC1C=CC=CC1(N)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.36
MAOA P21397 9/20 0.36
KDM1A O60341 6/20 0.33
PNMT P11086 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28537875 1.00 MAOB (0.36) MAOBMAOAKDM1APNMT
Urea SCHEMBL10593912 0.91 MAOB (0.32) MAOBMAOA
SCHEMBL28438820 0.82 ALDH1A1 (0.33)
SCHEMBL28445059 0.81
SCHEMBL30673902 0.81 MAOB (0.41) MAOBMAOAKDM1A
SCHEMBL28634401 0.81 MAOB (0.40) MAOBMAOA
SCHEMBL8752629 0.78 MAOB (0.32) MAOBMAOAKDM1APNMT
SCHEMBL2870312 0.77 MAOA (0.39) MAOBMAOAKDM1APNMT
SCHEMBL20840140 0.77 MAOB (0.45) MAOBMAOAKDM1A
SCHEMBL30561218 0.77 ALDH1A1 (0.34) MAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112390804-A Cyclopentachromanone spliced spiro-oxoindole compound and preparation method and application thereof 贵州大学 2021-02-23 CN claimed
JP-9151143-A None JP disclosed
CN-112390804-B Cyclopentachromanone spliced spiro-oxoindole compound and preparation method and application thereof 贵州大学 2022-05-24 CN disclosed
CN-109824948-B Rubber seal sizing material for capacitor printing and preparation method thereof 中国热带农业科学院农产品加工研究所 2021-08-17 CN disclosed
CN-112390804-A Cyclopentachromanone spliced spiro-oxoindole compound and preparation method and application thereof 贵州大学 2021-02-23 CN disclosed
CN-106726650-B Atomizing blister oxide hair dye composition 朋友株式会社 2018-05-11 CN disclosed
EP-1991514-B1 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2017-12-20 EP disclosed
CN-104755066-B Spray-type foam oxidation hair dye composition 朋友株式会社 2017-09-26 CN disclosed
CN-107167978-A Blue phase liquid crystal display, method of manufacturing the same, and chiral material used therefor 友达光电股份有限公司 2017-09-15 CN disclosed
CN-106726650-A Atomizing blister oxide hair dye composition 朋友株式会社 2017-05-31 CN disclosed
EP-1991514-A1 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG Chem, Ltd. (KR) 2008-11-19 EP disclosed
WO-2007102683-A1 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2007-09-13 WO disclosed
CN-1317274-C 1-phenyl-2-heteroaryl-substituted benzimdazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives SCHERING AG (DE) 2007-05-23 CN disclosed
EP-0901996-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES MITSUI CHEMICALS INC (JP) 2006-02-01 EP disclosed
CN-1633429-A 1-phenyl-2-heteroaryl substituted benzimidazole derivatives, their use for the preparation of medicaments and pharmaceutical compositions containing them SCHERING AG (DE) 2005-06-29 CN disclosed
US-6222072-B1 RACTING IMINE WITH HYDRIDE REAGENT IN PRESENCE OF OPTICALLY ACTIVE METAL COMPOUND, WHEREIN HYDRIDE REAGENT IS A METAL HYDRIDE, REAGENT THAT UNDERGOES METAL EXCHANGE, METAL TRIALKOXY HYDRIDE COMPLEX OR METAL(TRICARBOXYLIC ACID)HYDRIDE MITSUI CHEMICALS INC. (JP) 2001-04-24 US disclosed
EP-0901996-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES Mitsui Chemicals, Inc. (JP) 1999-03-17 EP disclosed
US-5756790-A FROM KETONES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-05-26 US disclosed
JP-H09151143-A NEW OPTICALLY ACTIVE COBALT (II) COMPLEX AND PRODUCTION OF OPTICALLY ACTIVE ALCOHOL MITSUI PETROCHEM IND LTD 1997-06-10 JP disclosed
US-4575478-A DURABILITY, BONDING STRENGTH TORAY INDUSTRIES (JP) 1986-03-11 US disclosed