Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341897 | 0.95 | CCNE1 (0.56) | CCNE1CDK2CDK5NPC1RAB9A | |
| SCHEMBL1343433 | 0.93 | NPC1 (0.53) | NPC1RAB9AKMT2ASMN1; SMN2TP53 | |
| SCHEMBL1343742 | 0.86 | CCNE1 (0.50) | CCNE1CDK2CDK5NPC1RAB9A | |
| SCHEMBL1343736 | 0.85 | CCNE1 (0.49) | CCNE1CDK2CDK5NPC1RAB9A | |
| SCHEMBL1343811 | 0.83 | RAB9A (0.47) | NPC1RAB9AKMT2ASMN1; SMN2TP53 | |
| SCHEMBL1341811 | 0.82 | SMN1; SMN2 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2TP53 | |
| SCHEMBL1340901 | 0.82 | NPC1 (0.46) | CCNE1CDK2CDK5NPC1RAB9A | |
| SCHEMBL1342400 | 0.81 | NPC1 (0.53) | CCNE1CDK2CDK5NPC1RAB9A | |
| SCHEMBL1343257 | 0.80 | TSHR (0.45) | CCNE1CDK2CDK5NPC1RAB9A | |
| SCHEMBL1342598 | 0.79 | CCNE1 (0.56) | CCNE1CDK2CDK5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |