Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649927 | 0.92 | GCK (0.38) | GCKCSNK1DMEN1RAB9AKMT2A | |
| SCHEMBL1342970 | 0.90 | GCK (0.41) | GCKCSNK1DMEN1RAB9AKMT2A | |
| SCHEMBL1342961 | 0.89 | MEN1 (0.39) | CSNK1DMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL1342962 | 0.87 | CSNK1D (0.40) | CSNK1DMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL1342969 | 0.87 | MEN1 (0.39) | CSNK1DMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL1343610 | 0.83 | CSNK1D (0.41) | CSNK1DMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL1342285 | 0.83 | CSNK1D (0.43) | GCKCSNK1DRAB9ANPC1SCN10A | |
| SCHEMBL2650841 | 0.83 | SMN1; SMN2 (0.32) | MEN1RAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL1342752 | 0.82 | MAPT (0.42) | CSNK1DMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL2652270 | 0.81 | GCK (0.35) | GCKGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |