Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
| ▸ | MAX | P61244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652271 | 0.92 | GCK (0.38) | GCKMKNK2MYCMAX | |
| SCHEMBL1343155 | 0.91 | GCK (0.41) | GCKMKNK2MYCMAX | |
| SCHEMBL1342712 | 0.90 | ALDH1A1 (0.35) | MKNK2GRM4MYCMAX | |
| SCHEMBL1342715 | 0.88 | MKNK2 (0.36) | GCKMKNK2 | |
| SCHEMBL1343153 | 0.88 | ALDH1A1 (0.36) | GCKMKNK2GRM4MYCMAX | |
| SCHEMBL2650841 | 0.85 | SMN1; SMN2 (0.32) | GRM4 | |
| SCHEMBL1343475 | 0.84 | GCK (0.42) | GCKMKNK2MYCMAX | |
| SCHEMBL2650118 | 0.83 | GCK (0.33) | GCKMKNK2GRM4 | |
| SCHEMBL1342440 | 0.83 | MYC (0.35) | MKNK2GRM4MYCMAX | |
| SCHEMBL1343008 | 0.82 | MAPT (0.38) | MYCMAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |