Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | HCN1 | O60741 | 1/20 | 0.31 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24357949 | 0.95 | MEN1 (0.37) | MEN1KMT2ASLC6A9HCN1HCN4 | |
| SCHEMBL12717845 | 0.95 | SLC6A9 (0.32) | MEN1KMT2ASLC6A9 | |
| SCHEMBL10865041 | 0.92 | SLC6A9 (0.38) | MEN1KMT2ASLC6A9HCN1HCN4 | |
| SCHEMBL10129209 | 0.92 | MEN1 (0.39) | MEN1KMT2ASLC6A9HCN1HCN4 | |
| SCHEMBL13197466 | 0.92 | MEN1 (0.39) | MEN1KMT2ASLC6A9HCN1HCN4 | |
| SCHEMBL28151536 | 0.92 | MEN1 (0.39) | MEN1KMT2ASLC6A9HCN1HCN4 | |
| SCHEMBL18180585 | 0.92 | SLC6A9 (0.37) | MEN1KMT2ASLC6A9KCNH2 | |
| SCHEMBL25558801 | 0.90 | — | — | |
| SCHEMBL25165171 | 0.90 | — | — | |
| SCHEMBL28767240 | 0.81 | SLC6A9 (0.33) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072188-A1 | KRAS G12D INHIBITORS AND USE THEREOF IN MEDICINE | 贝达药业股份有限公司 | 2023-05-04 | — | — | WO | disclosed |