Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.90 |
| ▸ | MAPT | P10636 | 1/20 | 0.90 |
| ▸ | RAB9A | P51151 | 6/20 | 0.87 |
| ▸ | NPC1 | O15118 | 6/20 | 0.87 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.65 |
| ▸ | CNR2 | P34972 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | VNN1 | O95497 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132031 | 1.00 | NPSR1 (0.90) | NPSR1MAPTRAB9ANPC1CTNNB1 | |
| SCHEMBL26499244 | 0.98 | NPSR1 (0.88) | NPSR1MAPTRAB9ANPC1CTNNB1 | |
| SCHEMBL4158804 | 0.93 | NPC1 (1.00) | NPSR1MAPTRAB9ANPC1CTNNB1 | |
| SCHEMBL4824992 | 0.91 | NPSR1 (0.74) | NPSR1MAPTRAB9ANPC1CTNNB1 | |
| SCHEMBL7816239 | 0.89 | SRD5A2 (0.81) | NPSR1MAPTRAB9ANPC1CTNNB1 | |
| SCHEMBL6658798 | 0.84 | MAPT (0.67) | NPSR1MAPTRAB9ANPC1CTNNB1 | |
| SCHEMBL31164296 | 0.84 | MAPT (0.67) | NPSR1MAPTRAB9ANPC1SRD5A2 | |
| SCHEMBL28128979 | 0.83 | CTNNB1 (0.70) | NPSR1MAPTRAB9ANPC1CTNNB1 | |
| Dalosirvat SCHEMBL653870 | 0.81 | CTNNB1 (1.00) | MAPTRAB9ANPC1CTNNB1ALDH1A1 | |
| SCHEMBL10027735 | 0.81 | CTNNB1 (0.82) | NPSR1MAPTRAB9ANPC1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787777-B1 | Crown ether amines and methods of use | PALL CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787777-B1 | Crown ether amines and methods of use | H1-2, H1-0, CNR1 | NPSR1 107/4885MAPT 2228/4885RAB9A 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.