SCHEMBL7816239

SCHEMBL7816239

O=C(c1ccccc1)c1ccc2c(c1)OCO2

nearest known ligand 0.81

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.81
NPC1 O15118 7/20 0.76
RAB9A P51151 7/20 0.76
MAPT P10636 3/20 0.73
NPSR1 Q6W5P4 1/20 0.73
CTNNB1 P35222 2/20 0.69
WNT3A P56704 1/20 0.69
ALDH1A1 P00352 1/20 0.68
MAPK1 P28482 1/20 0.68
PKM P14618 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
PTGS2 P35354 1/20 0.59
TDP1 Q9NUW8 1/20 0.57
HPGD P15428 1/20 0.55
TSHR P16473 1/20 0.55
GFER P55789 1/20 0.55
HSD17B10 Q99714 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4824941 0.91 SRD5A2 (0.82) SRD5A2NPC1RAB9AMAPTNPSR1
SCHEMBL6132031 0.89 NPSR1 (0.90) SRD5A2NPC1RAB9AMAPTNPSR1
SCHEMBL26499247 0.89 NPSR1 (0.90) SRD5A2NPC1RAB9AMAPTNPSR1
SCHEMBL26499244 0.88 NPSR1 (0.88) SRD5A2NPC1RAB9AMAPTNPSR1
SCHEMBL4158804 0.86 NPC1 (1.00) SRD5A2NPC1RAB9AMAPTNPSR1
SCHEMBL7475049 0.86 SRD5A2 (0.75) SRD5A2NPC1RAB9AMAPTNPSR1
SCHEMBL7532873 0.85 SRD5A2 (0.69) SRD5A2NPC1RAB9AMAPTNPSR1
SCHEMBL18546949 0.84 SRD5A2 (0.73) SRD5A2NPC1RAB9AMAPTNPSR1
SCHEMBL8961590 0.81 CTNNB1 (0.82) NPC1RAB9AMAPTCTNNB1WNT3A
SCHEMBL12098605 0.81 MAPT (0.72) NPC1RAB9AMAPTCTNNB1WNT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021093556-A1 METHOD FOR PREPARING HYDROXYL COMPOUND, DEUTERATED COMPOUND THEREOF, AND TRITIATED COMPOUND THEREOF 中国科学院福建物质结构研究所 2021-05-20 WO disclosed
EP-0704067-B1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG IND OHIO INC (US) 2001-08-01 EP disclosed
EP-0859763-A1 DIHYDROPHTHALAZINE ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS Bearsden Bio, Inc. (US) 1998-08-26 EP disclosed
EP-0704067-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1996-04-03 EP disclosed
EP-0704067-A4 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES INC (US) 1996-02-02 EP disclosed
US-5458815-A Photochromic naphthopyran compounds TRANSITIONS OPTICAL, INC. (US) 1995-10-17 US disclosed
US-5384077-A Naphthopyrans TRANSITIONS OPTICAL, INC. (US) 1995-01-24 US disclosed
WO-1995000866-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1995-01-05 WO disclosed
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3962415-A Insecticide evaporator comprising DDVP with synergized benzodioxole compound as stabilizer AIRWICK INDUSTRIES, INC. (US) 1976-06-08 US disclosed