Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26499270 | 1.00 | MAPT (0.75) | MAPTNPSR1KDM4EGAANPC1 | |
| SCHEMBL6658798 | 0.95 | MAPT (0.67) | MAPTNPSR1KDM4EGAANPC1 | |
| SCHEMBL4824992 | 0.85 | NPSR1 (0.74) | MAPTNPSR1KDM4ENPC1RAB9A | |
| SCHEMBL11618734 | 0.84 | MAPT (0.75) | MAPTNPSR1KDM4EGAANPC1 | |
| SCHEMBL26499247 | 0.80 | NPSR1 (0.90) | MAPTNPSR1KDM4ENPC1RAB9A | |
| SCHEMBL18072578 | 0.80 | TSHR (0.89) | MAPTNPSR1KDM4EGAANPC1 | |
| SCHEMBL6132031 | 0.80 | NPSR1 (0.90) | MAPTNPSR1KDM4ENPC1RAB9A | |
| SCHEMBL26499244 | 0.79 | NPSR1 (0.88) | MAPTNPSR1KDM4ENPC1RAB9A | |
| SCHEMBL31164296 | 0.79 | MAPT (0.67) | MAPTNPSR1KDM4ENPC1RAB9A | |
| SCHEMBL10031399 | 0.78 | KDM4E (0.72) | MAPTNPSR1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787777-B1 | Crown ether amines and methods of use | PALL CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787777-B1 | Crown ether amines and methods of use | PALL CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787777-B1 | Crown ether amines and methods of use | H1-2, H1-0, CNR1 | MAPT 2228/4885NPSR1 107/4885KDM4E 1744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.