Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26499327 | 0.88 | MEN1 (0.44) | HCAR1FGFR1DRD2DRD3KCNH2 | |
| SCHEMBL22349797 | 0.83 | PPARD (0.48) | CYP11B2KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22349850 | 0.82 | ALDH1A1 (0.47) | RAB9ASMN1; SMN2ALDH1A1PPARGPPARD | |
| SCHEMBL22349788 | 0.77 | ELANE (0.48) | CYP11B2ALDH1A1GAAMAPT | |
| SCHEMBL25160199 | 0.74 | PPARD (0.48) | HCAR1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL25160757 | 0.74 | PPARG (0.50) | KMT2AMGLLMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL22349793 | 0.73 | PPARD (0.48) | HCAR1CYP11B2RAB9ASMN1; SMN2PPARG | |
| SCHEMBL20644446 | 0.73 | PPARD (0.51) | MGLLPPARGPPARDPPARA | |
| SCHEMBL16196902 | 0.73 | PPARD (0.48) | HSP90AA1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL26499330 | 0.73 | HSD17B3 (0.39) | SMN1; SMN2ALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321082-A1 | USE OF TRIAZOLE ANALOGUES FOR INHIBITION OF A TRIPARTITE VOR PROTEIN COMPLEX IN MULTICELLULAR ORGANISMS | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| US-20230321082-A1 | USE OF TRIAZOLE ANALOGUES FOR INHIBITION OF A TRIPARTITE VOR PROTEIN COMPLEX IN MULTICELLULAR ORGANISMS | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321082-A1 | USE OF TRIAZOLE ANALOGUES FOR INHIBITION OF A TRIPARTITE VOR PROTEIN COMPLEX IN MULTICELLULAR ORGANISMS | RABL3, VAPA, VAPB | HCAR1 1369/4885FGFR1 4165/4885DRD2 3895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.