Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 4/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649953 | 0.91 | CCNE1 (0.37) | CCNE1CDK2CDK5MAPTGSK3B | |
| SCHEMBL1341881 | 0.88 | CCNE1 (0.39) | CCNE1CDK2CDK5ABL1KIT | |
| SCHEMBL1341634 | 0.87 | CCNE1 (0.39) | CCNE1CDK2CDK5MAPTGSK3B | |
| SCHEMBL1343840 | 0.81 | CCNE1 (0.37) | CCNE1CDK2CDK5ABL1RAB9A | |
| SCHEMBL1339883 | 0.80 | CCNE1 (0.38) | CCNE1CDK2CDK5MAPTGSK3B | |
| SCHEMBL1342923 | 0.79 | CCNE1 (0.36) | CCNE1CDK2CDK5MAPTABL1 | |
| SCHEMBL2650013 | 0.78 | KDM4C (0.34) | CCNE1CDK2CDK5ALDH1A1RAB9A | |
| SCHEMBL1342097 | 0.78 | CCNE1 (0.36) | CCNE1CDK2CDK5MAPTGSK3B | |
| SCHEMBL1341605 | 0.77 | CCNE1 (0.37) | CCNE1CDK2CDK5MAPTALDH1A1 | |
| SCHEMBL1342177 | 0.77 | CCNE1 (0.46) | CCNE1CDK2CDK5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |