Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.32 |
| ▸ | KDM6B | O15054 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341881 | 0.97 | CCNE1 (0.39) | CCNE1CDK2CDK5KDM4CABL1 | |
| SCHEMBL1341634 | 0.96 | CCNE1 (0.39) | CCNE1CDK2CDK5KDM4CABL1 | |
| SCHEMBL2649962 | 0.91 | CCNE1 (0.36) | CCNE1CDK2CDK5KDM4CABL1 | |
| SCHEMBL1342197 | 0.86 | ALDH1A1 (0.40) | CCNE1CDK2CDK5MAPT | |
| SCHEMBL1343840 | 0.84 | CCNE1 (0.37) | CCNE1CDK2CDK5KDM4CABL1 | |
| SCHEMBL1342360 | 0.83 | CCNE1 (0.39) | CCNE1CDK2CDK5KDM4CABL1 | |
| SCHEMBL1340218 | 0.83 | CDK5 (0.39) | CCNE1CDK2CDK5KDM4CABL1 | |
| SCHEMBL1339883 | 0.83 | CCNE1 (0.38) | CCNE1CDK2CDK5KDM4CABL1 | |
| SCHEMBL1340520 | 0.83 | CCNE1 (0.37) | CCNE1CDK2CDK5KDM4CMAPT | |
| SCHEMBL1340571 | 0.83 | ABCC1 (0.39) | MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |