Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 6/20 | 0.38 |
| ▸ | CDK2 | P24941 | 6/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341890 | 0.92 | CCNE1 (0.38) | CCNE1CDK2CDK5GSK3BCSNK2A1 | |
| SCHEMBL1341645 | 0.91 | CCNE1 (0.40) | CCNE1CDK2CDK5KDM4EL3MBTL1 | |
| SCHEMBL1340527 | 0.83 | KDR (0.38) | CCNE1CDK2CDK5GSK3BCSNK2A1 | |
| SCHEMBL1341301 | 0.81 | ALDH1A1 (0.38) | CCNE1CDK2CDK5MAPTMEN1 | |
| SCHEMBL1342197 | 0.79 | ALDH1A1 (0.40) | CCNE1CDK2CDK5MAPTMEN1 | |
| SCHEMBL1343849 | 0.79 | SMARCA2 (0.38) | CCNE1CDK2CDK5MAPTMEN1 | |
| SCHEMBL1339893 | 0.79 | CCNE1 (0.38) | CCNE1CDK2CDK5SMN1; SMN2 | |
| SCHEMBL1342122 | 0.79 | CCNE1 (0.35) | CCNE1CDK2CDK5MAPTKMT2A | |
| SCHEMBL1342173 | 0.79 | CCNE1 (0.33) | CCNE1CDK2CDK5GSK3BCSNK2A1 | |
| SCHEMBL1340228 | 0.78 | SMARCA2 (0.41) | CCNE1CDK2CDK5GSK3BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |