Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342550 | 0.95 | SMN1; SMN2 (0.42) | SMN1; SMN2FFAR2CCNE1CDK2CDK5 | |
| SCHEMBL1342884 | 0.93 | SMN1; SMN2 (0.44) | SMN1; SMN2LCKGAAKMT2AGCK | |
| SCHEMBL1341081 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2FFAR2CCNE1CDK2CDK5 | |
| SCHEMBL1342514 | 0.86 | CCNE1 (0.46) | SMN1; SMN2CCNE1CDK2CDK5GAA | |
| SCHEMBL1340869 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2FFAR2LCKGAAKMT2A | |
| SCHEMBL1343650 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2LCKGAAKMT2A | |
| SCHEMBL1342470 | 0.83 | CCNE1 (0.48) | SMN1; SMN2FFAR2CCNE1CDK2CDK5 | |
| SCHEMBL1342968 | 0.83 | MEN1 (0.40) | SMN1; SMN2CCNE1CDK2CDK5GAA | |
| SCHEMBL1343288 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2CCNE1CDK2CDK5LCK | |
| SCHEMBL1342158 | 0.81 | PKM (0.37) | SMN1; SMN2GAAGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |