⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484450 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27797668 | 0.98 | — | — | |
| SCHEMBL11414328 | 0.80 | HTR1A (0.33) | — | |
| SCHEMBL5627360 | 0.76 | — | — | |
| SCHEMBL2124905 | 0.76 | — | — | |
| SCHEMBL22413765 | 0.76 | SLC6A2 (0.34) | — | |
| SCHEMBL1620793 | 0.76 | — | — | |
| SCHEMBL2127211 | 0.76 | — | — | |
| SCHEMBL28162738 | 0.75 | — | — | |
| SCHEMBL28162737 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127839-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20230127839-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-04-27 | — | — | US | disclosed |
| CN-105294655-A | CDK small-molecule inhibitor compounds and application therefore | GUANGDONG HEC PHARMACEUTICAL | 2016-02-03 | — | — | CN | disclosed |
| CN-104926808-A | Dihydro-pyrimidine compound and application thereof in medicine | GUANGDONG HEC PHARMACEUTICAL | 2015-09-23 | — | — | CN | disclosed |
| CN-103626752-B | Dihydropyrimidine compound and application thereof in medicine | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2015-08-12 | — | — | CN | disclosed |
| CN-104098551-A | Substituted quinazoline derivative as aurora kinase inhibitor | GUANGDONG HEC PHARMACEUTICAL | 2014-10-15 | — | — | CN | disclosed |
| CN-103626752-A | Dihydropyrimidine compound and application thereof in medicine | GUANGDONG HEC PHARMACEUTICAL | 2014-03-12 | — | — | CN | disclosed |