Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 6/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341296 | 0.94 | KDM4C (0.41) | KDM4CCCNE1CDK2CDK5CNR1 | |
| SCHEMBL1342744 | 0.93 | ALDH1A1 (0.37) | CCNE1CDK2CDK5ALDH1A1ADORA3 | |
| SCHEMBL2650013 | 0.93 | KDM4C (0.34) | KDM4CCCNE1CDK2CDK5CNR1 | |
| SCHEMBL2650014 | 0.91 | CNR1 (0.35) | CCNE1CDK2CDK5CNR1ALDH1A1 | |
| SCHEMBL1340520 | 0.89 | CCNE1 (0.37) | KDM4CCCNE1CDK2CDK5CNR1 | |
| SCHEMBL1342558 | 0.88 | ALDH1A1 (0.38) | CCNE1CDK2CDK5CNR1ALDH1A1 | |
| SCHEMBL2650546 | 0.87 | CCNE1 (0.33) | KDM4CCCNE1CDK2CDK5CNR1 | |
| SCHEMBL1341301 | 0.84 | ALDH1A1 (0.38) | CCNE1CDK2CDK5CNR1ALDH1A1 | |
| SCHEMBL1342469 | 0.83 | MAPT (0.38) | ALDH1A1ADORA3RAB9AL3MBTL1GCK | |
| SCHEMBL1344736 | 0.83 | KDM4C (0.40) | KDM4CCCNE1CDK2CDK5CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |