SCHEMBL26500149

SCHEMBL26500149

Cc1cc(-c2cc3ccccc3s2)sc1-c1nc2sc(-c3sc(-c4cc5ccccc5s4)cc3C)nc2s1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.41
APP P05067 2/20 0.41
CYP19A1 P11511 1/20 0.40
TNIK Q9UKE5 1/20 0.38
GRM5 P41594 1/20 0.38
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
CA1 P00915 2/20 0.36
CA9 Q16790 2/20 0.36
CA2 P00918 1/20 0.36
NQO1 P15559 1/20 0.36
NQO2 P16083 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
ERN1 O75460 1/20 0.35
STK17B O94768 1/20 0.35
HIPK4 Q8NE63 1/20 0.35
STK17A Q9UEE5 1/20 0.35
FYN P06241 1/20 0.35
CHRM2 P08172 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26500159 0.80 APP (0.50) APPCYP19A1HSD17B1HSD17B2CA1
SCHEMBL290152 0.79 SMN1; SMN2 (0.53) CA1CA9CA2STK17BSTK17A
SCHEMBL26500221 0.78 APP (0.45) APPCYP19A1HSD17B1HSD17B2CA1
SCHEMBL289540 0.74 KDM4E (0.54) TNIK
SCHEMBL845603 0.74 APP (0.63) APPCYP19A1HSD17B1HSD17B2CA1
SCHEMBL29732980 0.74 APP (0.63) APPCYP19A1HSD17B1HSD17B2CA1
SCHEMBL2149612 0.70 APP (0.59) APPCYP19A1HSD17B1HSD17B2CA1
SCHEMBL5148513 0.68 APP (0.57) APPCYP19A1HSD17B1HSD17B2CA1
SCHEMBL27651550 0.68 APP (0.57) APPCYP19A1HSD17B1HSD17B2CA1
SCHEMBL2150464 0.68 APP (0.57) APPCYP19A1HSD17B1HSD17B2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132579-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
US-20230132579-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed