Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.63 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.52 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845603 | 1.00 | APP (0.63) | APPHSD17B1HSD17B2CA9CA2 | |
| SCHEMBL2149612 | 0.95 | APP (0.59) | APPHSD17B1HSD17B2CA9CA2 | |
| SCHEMBL5148513 | 0.93 | APP (0.57) | APPHSD17B1HSD17B2CA9CA2 | |
| SCHEMBL27651550 | 0.93 | APP (0.57) | APPHSD17B1HSD17B2CA9CA2 | |
| SCHEMBL2150464 | 0.93 | APP (0.57) | APPHSD17B1HSD17B2CA9CA2 | |
| SCHEMBL32677328 | 0.87 | APP (0.81) | APPHSD17B1HSD17B2CA9CA2 | |
| SCHEMBL27989389 | 0.87 | APP (0.57) | APPHSD17B1HSD17B2CA9CA2 | |
| SCHEMBL27159530 | 0.87 | APP (0.81) | APPHSD17B1HSD17B2CA9CA2 | |
| SCHEMBL19133572 | 0.87 | APP (0.57) | APPHSD17B1HSD17B2CA9CA2 | |
| SCHEMBL12854022 | 0.85 | APP (0.55) | APPHSD17B1HSD17B2CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383870-A1 | HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. | 2024-11-21 | — | — | US | disclosed |
| US-20240116965-A1 | ORGANOMETALLIC COMPOUNDS | UMICORE AG & CO. KG (DE) | 2024-04-11 | — | — | US | disclosed |
| EP-4267591-A2 | ORGANOMETALLIC COMPOUNDS | Umicore AG & Co. KG (DE) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022136049-A2 | ORGANOMETALLIC COMPOUNDS | UMICORE AG & CO. KG (DE) | 2022-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116965-A1 | ORGANOMETALLIC COMPOUNDS | DDT, PPOX, PDCD2L | APP 4139/4885HSD17B1 3742/4885HSD17B2 3574/4885 |
| US-20240383870-A1 | HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF | ALDH1A2, ALDH2, SSB | APP 1636/4885HSD17B1 988/4885HSD17B2 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.