Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751846 | 0.76 | MAPT (0.57) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2650033 | 0.72 | NPC1 (0.48) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21957648 | 0.72 | HDAC8 (0.54) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8854984 | 0.72 | KMT2A (0.43) | ERN1BCHEGLRA1 | |
| SCHEMBL5239013 | 0.72 | LOXL2 (0.47) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25146420 | 0.71 | MAPK1 (0.53) | MAPTL3MBTL1SMN1; SMN2RAB9AHTR1A | |
| SCHEMBL3923636 | 0.71 | MAPT (0.66) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17833748 | 0.70 | HPGD (0.50) | MAPTSMN1; SMN2NPC1RAB9ACTSV | |
| SCHEMBL28503954 | 0.70 | PDE4A (0.48) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17833744 | 0.70 | CHRNA7 (0.47) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |