Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341158 | 0.98 | MAPT (0.39) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1340598 | 0.94 | KMT2A (0.39) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1341439 | 0.90 | RAB9A (0.39) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1342772 | 0.90 | MAPT (0.38) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1342721 | 0.90 | MAPT (0.38) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1339994 | 0.89 | MAPT (0.37) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1340162 | 0.88 | MAPT (0.36) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1343364 | 0.88 | MAPT (0.42) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1342635 | 0.88 | MAPT (0.37) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1340889 | 0.88 | CSNK1D (0.37) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |