Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26501224 | 0.82 | CHRM2 (0.45) | ALDH1A1KCNH2POLBKCNQ3KCNQ2 | |
| SCHEMBL25543788 | 0.81 | KCNQ3 (0.36) | ALDH1A1KCNQ3KCNQ2CYP3A4CYP2D6 | |
| SCHEMBL25547807 | 0.81 | HSD17B10 (0.40) | KCNQ3KCNQ2CHRM3CHRM5DEGS1 | |
| SCHEMBL24637165 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KCNH2POLBCACNA1ICYP3A4 | |
| SCHEMBL26504808 | 0.78 | BCHE (0.36) | KCNH2POLBCACNA1IKCNQ3KCNQ2 | |
| SCHEMBL25547808 | 0.76 | GSK3B (0.38) | ALDH1A1PKMALOX15MEN1KMT2A | |
| SCHEMBL26501276 | 0.75 | CHRM3 (0.35) | KCNH2KCNQ3KCNQ2CHRM3CHRM5 | |
| SCHEMBL24240905 | 0.74 | KCNH2 (0.43) | ALDH1A1KCNH2POLBCACNA1ICYP3A4 | |
| SCHEMBL24492523 | 0.74 | KCNQ3 (0.34) | KCNQ3KCNQ2 | |
| SCHEMBL4086161 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KCNH2POLBCACNA1ICYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | KRAS, MDM2, NRAS | ALDH1A1 3243/4885KCNH2 4868/4885POLB 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.