Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 13/20 | 0.92 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19748515 | 0.96 | PANK3 (1.00) | PANK3TRPV1KDM4EALDH1A1MAPT | |
| SCHEMBL26502492 | 0.86 | PANK3 (0.82) | PANK3TRPV1KDM4EPKMALDH1A1 | |
| SCHEMBL21406301 | 0.86 | PANK3 (0.92) | PANK3 | |
| SCHEMBL26501474 | 0.85 | PANK3 (0.80) | PANK3TRPV1KDM4EALDH1A1MAPT | |
| SCHEMBL21406284 | 0.84 | PANK3 (1.00) | PANK3TRPV1 | |
| SCHEMBL21423908 | 0.84 | PANK3 (0.79) | PANK3TRPV1 | |
| SCHEMBL26502500 | 0.84 | PANK3 (0.79) | PANK3TRPV1KDM4EALDH1A1MAPT | |
| SCHEMBL21406318 | 0.84 | PANK3 (1.00) | PANK3TRPV1 | |
| SCHEMBL21423770 | 0.84 | PANK3 (0.78) | PANK3TRPV1KDM4EPKM | |
| SCHEMBL21406478 | 0.84 | PANK3 (0.78) | PANK3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321092-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321092-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | HMGCR, GCDH, CYP11A1 | PANK3 1573/4885TRPV1 4795/4885KDM4E 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.