SCHEMBL2650154

SCHEMBL2650154

C=CCN(CC=C)C(C)[O]

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321521 0.77
SCHEMBL1137481 0.77 MEN1 (0.33) MEN1KMT2A
Iodide SCHEMBL28162072 0.74 MEN1 (0.32) MEN1KMT2A
Bromide SCHEMBL28162642 0.74 MEN1 (0.32) MEN1KMT2A
Hydrochloric Acid SCHEMBL5269910 0.74 MEN1 (0.32) MEN1KMT2A
Water SCHEMBL31456290 0.74 MEN1 (0.32) MEN1KMT2A
SCHEMBL369394 0.74
SCHEMBL10525369 0.74
SCHEMBL15284734 0.74 MEN1 (0.30) MEN1KMT2A
SCHEMBL9832205 0.74 MEN1 (0.31) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730148-A4 AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS ABBOTT LAB (US) 2009-08-19 EP claimed
EP-1730148-A2 AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS Abbott Laboratories (US) 2006-12-13 EP claimed
US-20060025383-A1 Aminobenzoxazoles as therapeutic agents ABBOTT LABORATORIES 2006-02-02 US claimed
WO-2005074603-A2 AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS ABBOTT LABORATORIES (US) 2005-08-18 WO claimed
EP-0979228-A4 NOVEL CANNABINOID RECEPTOR AGONISTS SMITHKLINE BEECHAM CORP (US) 2000-05-03 EP claimed
EP-0979228-A1 NOVEL CANNABINOID RECEPTOR AGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2000-02-16 EP claimed
US-5843905-A Peptidic phosphinyloxymethyl ketones as interleukin-1β-converting enzyme inhibitors VERTEX PHARMACEUTICALS, INCORPORATED (US) 1998-12-01 US claimed
WO-1998041519-A1 NOVEL CANNABINOID RECEPTOR AGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1998-09-24 WO claimed
EP-0644197-B1 Peptidic phosphinyloxymethyl ketones as interleukin-1beta-converting enzyme inhibitors VERTEX PHARMA (US) 1998-09-09 EP claimed
US-5677283-A α-heteroaryloxymethyl ketones as interleukin - 1 β converting enzyme inhibitors SANOFI (FR) 1997-10-14 US claimed
EP-0644198-A1 Alpha-heteroaryloxymethyl ketones as interleukin-1beta converting enzyme inhibitors STERLING WINTHROP INC. (US) 1995-03-22 EP claimed
EP-0644197-A1 Peptidic phosphinyloxymethyl ketones as interleukin-1beta-converting enzyme inhibitors STERLING WINTHROP INC. (US) 1995-03-22 EP claimed
EP-0121171-B1 FUNGICIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE BAYER AG (DE) 1989-05-10 EP claimed
EP-0121171-A2 Fungicides, process for their preparation and their use BAYER AG (DE) 1984-10-10 EP claimed
EP-0105166-A1 Substituted tert. butanol derivatives, method for their preparation and antimycotic agents containing them BAYER AG (DE) 1984-04-11 EP claimed
US-8765789-B2 2-pyridinecarboxamide derivatives MSD K.K. (JP) 2014-07-01 US disclosed
US-20130085156-A1 NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES MSD K.K. (JP) 2013-04-04 US disclosed
US-4127662-A ANTIACNE SCHERING CORPORATION (US) 1978-11-28 US disclosed
US-4123433-A ANTIACNE AGENTS SCHERING CORPORATION (US) 1978-10-31 US disclosed
US-4044140-A Trityl picolinic acid derivatives and their use as anti-acne agents SCHERING CORPORATION (US) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060025383-A1 Aminobenzoxazoles as therapeutic agents ABL1, MAP3K19, MAP3K20 MEN1 2995/4885KMT2A 261/4885ALDH1A1 1952/4885
US-20130085156-A1 NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES GCKR, GCK, HK2 MEN1 4502/4885KMT2A 1297/4885ALDH1A1 1207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.