Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819855 | 0.92 | — | — | |
| SCHEMBL2650219 | 0.87 | GRM4 (0.32) | GRM4 | |
| SCHEMBL1342832 | 0.87 | GRM4 (0.33) | GRM4 | |
| SCHEMBL2650039 | 0.84 | GAA (0.31) | — | |
| SCHEMBL2651114 | 0.83 | — | — | |
| SCHEMBL1342251 | 0.82 | ALDH1A1 (0.33) | GRM4 | |
| SCHEMBL2651015 | 0.82 | CASR (0.33) | — | |
| SCHEMBL1342444 | 0.80 | GRM4 (0.31) | GRM4 | |
| SCHEMBL4819863 | 0.79 | NTRK1 (0.33) | GRM4 | |
| SCHEMBL1339918 | 0.79 | NPC1 (0.33) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |