Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | QRFPR | Q96P65 | 3/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25499007 | 1.00 | OPRD1 (0.48) | OPRD1OPRM1OPRK1CTSBREN | |
| SCHEMBL31090028 | 0.92 | OPRD1 (0.52) | OPRD1OPRM1OPRK1 | |
| SCHEMBL25654696 | 0.88 | OPRD1 (0.45) | OPRD1OPRM1OPRK1CTSBREN | |
| SCHEMBL25494728 | 0.88 | OPRD1 (0.45) | OPRD1OPRM1OPRK1CTSBREN | |
| SCHEMBL24406249 | 0.85 | ACE (0.43) | OPRD1OPRM1OPRK1CTSBREN | |
| SCHEMBL26502253 | 0.84 | OPRD1 (0.42) | OPRD1OPRM1OPRK1CTSBREN | |
| SCHEMBL26502186 | 0.84 | OPRD1 (0.42) | OPRD1OPRM1OPRK1CTSBREN | |
| SCHEMBL25495062 | 0.84 | QRFPR (0.42) | OPRD1OPRM1OPRK1CTSBCTSL | |
| SCHEMBL31365053 | 0.84 | QRFPR (0.42) | OPRD1OPRM1OPRK1CTSBCTSL | |
| SCHEMBL27370284 | 0.83 | OPRD1 (0.48) | OPRD1OPRM1OPRK1CTSBREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178641-A1 | DNA TOXIC DIMER COMPOUND AND CONJUGATE THEREOF | 成都百利多特生物药业有限责任公司 | 2023-09-28 | — | — | WO | disclosed |