Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TUBB8B | A6NNZ2 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273869 | 1.00 | NPC1 (0.60) | NPC1KMT2AMEN1PKMKDM4E | |
| SCHEMBL273626 | 0.90 | KMT2A (0.62) | NPC1KMT2AMEN1PKMKDM4E | |
| SCHEMBL266792 | 0.90 | KMT2A (0.62) | NPC1KMT2AMEN1PKMKDM4E | |
| SCHEMBL273256 | 0.89 | NPC1 (0.60) | NPC1KMT2AMEN1PKMKDM4E | |
| SCHEMBL268158 | 0.89 | NPC1 (0.60) | NPC1KMT2AMEN1PKMKDM4E | |
| SCHEMBL266828 | 0.86 | GAA (0.48) | NPC1KMT2AMEN1PKMKDM4E | |
| SCHEMBL273719 | 0.86 | GAA (0.48) | NPC1KMT2AMEN1PKMKDM4E | |
| SCHEMBL273286 | 0.85 | NPC1 (0.58) | NPC1KMT2AMEN1PKMKDM4E | |
| SCHEMBL268693 | 0.85 | NPC1 (0.58) | NPC1KMT2AMEN1PKMKDM4E | |
| SCHEMBL266600 | 0.84 | NPC1 (0.67) | NPC1KMT2AMEN1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134015-B2 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |