Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SLC34A2 | O95436 | 1/20 | 0.46 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.46 |
| ▸ | SLC34A3 | Q8N130 | 1/20 | 0.46 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273719 | 1.00 | GAA (0.48) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL274298 | 0.90 | RAB9A (0.54) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL266761 | 0.90 | RAB9A (0.54) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL273869 | 0.86 | NPC1 (0.60) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL265031 | 0.86 | NPC1 (0.60) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL267441 | 0.85 | GAA (0.47) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL273872 | 0.85 | GAA (0.47) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL269054 | 0.85 | CYP2D6 (0.55) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL269055 | 0.85 | CYP2D6 (0.55) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL268120 | 0.85 | MEN1 (0.51) | GAAMGAMSIMGAM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134015-B2 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |