Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.55 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650488 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PLCG2 | |
| SCHEMBL4368683 | 0.86 | CSNK2A2 (0.51) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PLCG2 | |
| SCHEMBL4368676 | 0.86 | CSNK2A2 (0.51) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PLCG2 | |
| SCHEMBL4365406 | 0.82 | KMT2A (0.58) | ALDH1A1CSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL4365408 | 0.82 | KMT2A (0.58) | ALDH1A1CSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL832924 | 0.81 | CSNK2A2 (0.48) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PLCG2 | |
| SCHEMBL832923 | 0.81 | CSNK2A2 (0.48) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PLCG2 | |
| SCHEMBL6797933 | 0.79 | PLCG2 (0.67) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PLCG2 | |
| SCHEMBL6797935 | 0.79 | PLCG2 (0.67) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PLCG2 | |
| SCHEMBL6802454 | 0.78 | CSNK2A2 (0.81) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PLCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015757-A1 | Novel Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | US | disclosed |
| WO-2005058845-A2 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015757-A1 | Novel Glucagon Antagonists/Inverse Agonists | GLP1R, GCGR, GIPR | ALDH1A1 4836/4885CSNK2A2 2787/4885CSNK2B 2084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.