Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 13/20 | 0.40 |
| ▸ | HTR2A | P28223 | 10/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015072 | 0.78 | HTR2C (0.43) | HTR2CADRB1HTR2BHTR2A | |
| SCHEMBL5228097 | 0.76 | HTR2C (0.40) | HTR2CADRB1HTR2BHTR2A | |
| SCHEMBL434850 | 0.72 | HTR2C (0.44) | HTR2CADRB1HTR2BHTR2A | |
| SCHEMBL2649431 | 0.72 | HTR2C (0.41) | HTR2CADRB1 | |
| SCHEMBL18284815 | 0.70 | TAAR1 (0.44) | HTR2CHTR2BHTR2A | |
| SCHEMBL20677321 | 0.68 | DPP4 (0.30) | — | |
| SCHEMBL15824978 | 0.67 | TAAR1 (0.43) | HTR2CHTR2BHTR2A | |
| SCHEMBL28587092 | 0.64 | HTR2C (0.52) | HTR2CHTR2BHTR2A | |
| SCHEMBL18284660 | 0.64 | TACR1 (0.48) | HTR2CHTR2BHTR2A | |
| SCHEMBL26530980 | 0.64 | HTR2C (0.80) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |