Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.43 |
| ▸ | HTR2B | P41595 | 6/20 | 0.43 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | TACR1 | P25103 | 10/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15824978 | 0.89 | TAAR1 (0.43) | HTR2CHTR2BHTR2ATACR1 | |
| SCHEMBL669693 | 0.80 | HTR2C (0.50) | HTR2CHTR2BHTR2A | |
| SCHEMBL15824963 | 0.80 | HTR2C (0.40) | HTR2CHTR2BHTR2A | |
| SCHEMBL2650583 | 0.78 | HTR2C (0.41) | HTR2CHTR2BHTR2AADRB1 | |
| SCHEMBL14698726 | 0.78 | HTR2C (0.54) | HTR2CHTR2BHTR2AADRB1 | |
| SCHEMBL30593287 | 0.78 | HTR2C (0.54) | HTR2CHTR2BHTR2AADRB1 | |
| Dimethylamine SCHEMBL27980772 | 0.77 | HTR2C (0.47) | HTR2CHTR2BHTR2A | |
| SCHEMBL18284815 | 0.77 | TAAR1 (0.44) | HTR2CHTR2BHTR2ATACR1 | |
| SCHEMBL1693684 | 0.76 | HTR2C (0.42) | HTR2CHTR2BHTR2ATACR1ADRB1 | |
| SCHEMBL30718523 | 0.76 | ADRB1 (0.43) | HTR2CHTR2BHTR2AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |